LIBRO + ANEXOS NEUMOLOGÍA PEDIÁTRICA

Neumología Pediátrica. Anexos ❚ 161 3. Side effects of therapy f. Prognosis 1. Natural history 2. Prognosis with therapy 4. Pulmonary hypertension a. Epidemiology 1. Recognize the clinical conditions that predispose a child to pulmonary hypertension b. Etiology/genetics 1. Know the role of bone morphogenic protein receptor 2(BMP-R2) c. Pathophysiology 1. Pathology a. Recognize the features of structural remodeling of the pulmonary vascular bed associated with pulmonary hypertension due to chronic hypoxemia b. Know the pathophysiologic consequences of persistent pulmonary hypertension of the newborn 2. Path mechanisms and consequences a. Recognize the gas exchange abnormalities associated with pulmonary hypertension b. Recognize the effects of pulmonary hypertension on cardiac function at rest d. Diagnosis and clinical manifestations 1. History a. Recognize the symptoms associated with primary pulmonary hypertension and that most patients are asymptomatic b. Recognize the clinical features of conditions associated with pulmonary hypertension (chronic thromboembolic events, pulmonary fibrosis, congestive heart disease, etc.) 2. Physical examination a. Recognize physical findings typical of primary pulmonary hypertension 3. Imaging a. Recognize radiographic findings associated with primary pulmonary hypertension 4. Pulmonary function tests 5. Other investigations 6. Diagnostic criteria a. Know the cardiac catheterization indices that separate pulmonary hypertension due to pulmonary vessel disease from that due to cardiac disorders b. Know the hemodynamic criteria for diagnosing pulmonary hypertension 7. Complications a. Recognize the clinical complications associated with pulmonary hypertension e. Prevention and therapeutic approach 1. Prevention 2. Therapeutic approach