LIBRO + ANEXOS NEUMOLOGÍA PEDIÁTRICA

Neumología Pediátrica. Anexos ❚ 199 h. Understand the importance of bronchial blood flow to the trachea and bronchi in transplanted lungs i. Know the complications of lung transplantation j. Understand that the bronchial airways are denervated following heart-lung or lung transplantation P. Tracheostomy 1. Indications a. Recognize the clinical indications for tracheostomy in children 2. Complications a. Recognize the immediate postoperative complications of tracheostomy b. Implement appropriate therapeutic steps when a child with a tracheostomy suddenly becomes cyanotic or has other signs and symptoms of acute hypoventilation c. Recognize the chronic complications of tracheostomy d. Recognize that a child younger than 1 year of age who has a tracheostomy because of severe subglottic stenosis is at risk for increased mortality during the first year after birth e. Recognize that aspiration secondary to dysfunctional swallowing may complicate tracheostomy f. Know the indications and contraindications of speaking valves in children with tracheostomy 3. Clinical effects a. Know how to confirm airway adequacy prior to decannulation in a child with a tracheostomy Q. Dornase alfa 1. Indications a. Understand the indications for the use of nebulized dornase alfa 2. Mechanism of action a. Know the mechanism of action of dornase alfa 3. Clinical effects a. Know that dornase alfa improves lung function in patients with cystic fibrosis and mild to moderate lung disease 4. Toxicity and side effects a. Know the common side effects of dornase alfa R. Miscellaneous 1. Understand that dopamine increases peripheral vascular resistance and that dobutamine decreases peripheral vascular resistance 2. Know the medications that increase respiratory drive 3. Know that nitric oxide is a potent vasodilator 4. Know that nitric oxide modulates interactions between inflammatory cells and vascular epithelium 5. Know that nitric oxide may improve ventilation/perfusion mismatch and reduce pulmonary artery pressure 6. Know that nitric oxide use requires accurate measurement of NO concentration, careful titration to the lowest effective concentration, and gradual termination 4. Prevention